Interferon treatment of condyloma

In life, everyone is familiar with genital warts. Generally, this sexually transmitted disease is caused by unclean sexual life. If you suffer from genital warts, you must pay attention to it and go to a regular hospital as soon as possible to choose the correct method to treat genital warts. There are many methods and drugs for treating genital warts. Among them, the most common drug treatment is interferon treatment. Interferon treatment for genital warts is a type of drug treatment. What is the effect of interferon treatment for genital warts?

How effective is interferon in treating condyloma acuminatum?

1 First of all, it can be clearly told to the patients that although interferon is widely used in the treatment of genital warts, the treatment effect is worrying. This is because interferon treatment of genital warts only inhibits the activity of the virus to a certain extent, but has no effect on the virus turning negative. Therefore, patients should choose carefully during treatment.

2 There are many methods for treating condyloma acuminatum at present, including physical therapy, drug therapy, comprehensive treatment, etc. Physical therapy is treated by physical excision. This therapy includes freezing, laser, surgery, photodynamic therapy, etc. It is a physical way to promote the shedding of warts. However, it has no effect on the conversion of the virus to negative. Therefore, it is not recommended for use in treatment.

3 Comprehensive treatment is more common. It means that patients need to cooperate with drug therapy and physical resection therapy during treatment. Physical resection is used to achieve the effect of clinical symptom treatment, while drugs can inhibit the activity of the virus to a certain extent, thereby effectively controlling the disease and avoiding recurrence.

Note:

TCM diagnostic criteria:

This disease is caused by the combination of damp-heat, wind toxins and qi and blood. Qi and blood stagnate at the junction of the skin and membrane, which leads to the formation of warts. The treatment should focus on detoxification. The clinical classification is based on damp-heat, wind-toxicity and other symptoms.

Damp-heat and wind poison:

Main symptoms: Papillary papules scattered or fused into patches at the junction of the pudendal membranes, with an itchy sensation, accompanied by frequent urination, urgency, and pain, as well as pus discharge from the urethral and vaginal orifices, increased leucorrhea, and even purulent leucorrhea. The tongue is pale, the tongue coating is white, and the pulse is floating, slightly rapid, or stringy and rapid.

Analysis: The patient has damp-heat in the liver and gallbladder, and is infected with wind-toxicity. The damp-heat and wind-toxicity damage the Qi and blood, and they stagnate and do not dissipate, resulting in the appearance of warts. Damp-heat in the liver and gallbladder flows downward to the lower part of the body, causing itching, pain, and stranguria; dampness and toxicity are intertwined, causing pus to overflow from the urethra. The tongue and pulse conditions are both signs of wind poison on the surface.

Western medicine diagnostic criteria:

The following diagnostic criteria can be used for this disease:

1. Symptoms: Mild itching and pressure in the vulva.

2. Physical signs: At the junction of the vulvar skin and mucous membrane, there are many light red, dark red or dirty gray wart-like structures on the surface of the lesion, which are uneven and sometimes fused into a cauliflower shape.

3. Pathological examination: Microscopically, papillary hyperplasia of the squamous epithelium and proliferation of the spinous cells were observed.

The above three aspects should generally be seen at the same time to make a diagnosis.

Western medicine diagnosis basis:

The diagnosis can be made based on medical history, clinical manifestations, physical examination and pathological examination. The diagnosis is mainly based on medical history, other symptoms of syphilis, finding Treponema pallidum in local exudate (dark field microscopy), and syphilis serological test. After the diagnosis was confirmed, adequate penicillin treatment was given, and the rash disappeared quickly without leaving any scars.

Western medicine differential diagnosis:

1. Villous labia minora, also known as pseudo-condyloma, often occurs on the inner side of the labia minora, vaginal vestibule and around the urethral orifice of young women. It appears as symmetrical and densely distributed small white or light red papules with a diameter of 1 to 2 mm. The surface is smooth and some may appear villous, caviar-like or polyp-like. There are no obvious subjective symptoms, and there is occasional itching. The acetic acid white test was negative.

2. Pearly penile papules The rash is located at the edge of the coronal sulcus of the glans penis. Pearly, conical or irregular white, yellowish-white or skin-colored papules can be seen. They may be translucent, with a smooth surface and a hard texture. The papules do not fuse with each other and are regularly arranged in one to several rows along the coronal sulcus. The acetic acid white test was negative.

3. Sebaceous gland ectopia: Millet-sized, isolated, slightly raised, yellow-white or light yellow papules in groups or patches may be seen on the glans penis, inside the foreskin or labia minora, with no subjective symptoms. The histological feature is that each papule is composed of a group of small mature sebaceous lobules, which surround the sebaceous duct. The acetic acid white test was negative.

4. Parafrenulum papular fibroma is a type of white or yellowish-white millet-sized papules that occur symmetrically on both sides of the frenulum. They may be single or multiple, soft in texture, smooth in surface, and not fused together. It can be differentiated from genital warts based on medical history and negative acetic acid white test.

5. Lichen lustrous is a shiny polygonal or round flat-topped papule that occurs on the penis shaft. It ranges from the size of a needle tip to a millet grain. It can be densely distributed but does not fuse with each other. Its pathological changes are characteristic.

6. Flat warts are secondary syphilis rashes, which are papules or plaques occurring in the genital area. The surface is flat and moist, and may also be granular or cauliflower-shaped. Treponema pallidum can be detected in dark field examination, and the syphilis serological reaction is positive.

7. Bowenoid papulosis The skin lesions are gray-brown or reddish-brown flat papules, most of which are multiple, round or irregular in shape. The surface of the papules may have a velvety appearance or be slightly keratinized and wart-like. In men, it is more common on the penis, scrotum and glans, and in women, it is more common on the labia minora and around the anus. Generally no symptoms. Histopathological examination can help in differentiation.

8. Syringomas appear as small, firm skin-colored or brown papules, several millimeters in diameter, multiple in number, and usually asymptomatic. Histopathological examination can confirm the diagnosis.

9. Genital squamous cell carcinoma is more common in people over 40 years old. The lesions are lumps or plaques with obvious infiltration, hard texture, easy bleeding, and often form ulcers. The diagnosis can be confirmed by histopathological examination.

10. Pseudo-condyloma: The lesions are small, miliary-sized, fish-egg-shaped, light red papules or villous changes limited to the labia minora. The surface of the lesions is smooth, the acetic acid white test is negative, and there are no diagnostically significant concave cells in pathology.